Swine industry is one of the biggest in our country and in other countries as well.  Pork has become the most consumed meat in the Philippines.  Different genes are being studied in relevance to productivity traits and one often studied in the ob gene.  Ob gene is also known as leptin gene which came from the study thrifty genotype.  Leptin came from Greek work “Leptos” which means thin.  Thrifty genotype states that body fat is regulated by the involvement of upper and lower systems wherein upper intervention is the risk of predation while the lower intervention is the risk of starvation.  This study used hair follicles collected from 52 large white and 27 landrace and their offspring.  Using the modified SolGent Genomic DNA prep kit Protocol, Genomic DNA was extracted.  The PCR-RFLP, protocol from Jiang and Gibson (1998) using Hinfl endonuclease was followed by leptin genotyping.  Power Marker and SAS were used to analyze the date then gene diversity, major allele frequency, heterozygosity and PIC were obtained.  Samples 1-24 showed that bands present are around 460 bp long.  The samples with detected region were subjected to PCR-FRLP.  Bands for genotype T/T, T/C and C/C have genotypic frequencies of 0.7754, 0.2139 and 0.0107, respectively.  Fragment T/T was found with 460 bp long, T/C has 480 bp, 360 bp and 110 bp and C/C has bands with 360 and 110 bp long.  Using the p-values (from SAS) it showed that breed and genotype have no significant effect on the ADG, TPB, PBA and ABW.