The goal of the study was to determine if LEPR-HpaII gene polymorphism has any effect on back fat thickness and some reproductive traits in sows. LEPR is a candidate gene for backfat thickness in pigs. Backfat as a form of energy reserve is important for nursing its piglets and prepare itself for the next breeding. DNA template was isolated from hair samples of 31 sows. PCR-RFLP method was used to study LEPR-HpaII gene polymorphism which have two alleles: A (2000 bp fragment) and B (1450 and 550 bp fragment). The findings show that in the Landrace population of breeder farm, the A allele (0.6) is more frequent than the B allele (0.4) and the AB (0.61) genotype is more frequent than the AA (0.29) and BB (0.1) genotypes. Data analysis show that the LEPR-HpaII gene polymorphism has significant effect only on backfat thickness 21 days after furrowing (BFT21D) with the AA genotype having the thickest backfat (12 ± 0.73 mm). Although not statistically significant, consistently genotype AA of LEPR-HpaII gene polymorphism obtained thicker BFTFRW, higher LSBA, LSW, WWT, BWT and shorter WEI. Hence this genotype should still be considered for further research in a farm where there is no foster parenting practice.